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SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8.7
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Magnesium (from Magnesium Aspartate)
250 mg
60%
Potassium (from Potassium Aspartate)
99 mg
2%
Taurine (Free-Form)
100 mg
†
Top Medical Research Studies
8
Magnesium boosts colonic activity
Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome.
Direct focus on IBS treatment
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Read More
8
Bile acid sequestrant A3384 shows promise
Effects of conventional and a novel colonic-release bile acid sequestrant, A3384, on fibroblast growth factor 19 and bile acid metabolism in healthy volunteers and patients with bile acid diarrhoea.
Relevant research on BAD treatment
We investigated how a novel colonic-release formulation of colestyramine, A3384, impacts bile acid metabolism and bowel function in patients with primary bile acid diarrhoea (BAD).
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
Read More
Most Useful Reviews
9.5
Reduced cramps
Magnesium and potassium support heart health, but I've found they help with my autoimmune disease. As I'm on prednisolone, I face side effects like cramps and constipation. Magnesium and potassium aspartate eased my cramps, improved my bowel function, and helped my sleep. I take two capsules at night with a light meal and highly rate this product.
Read More
9.5
Sleep improvement
Magnesium and potassium support heart function, but they greatly help my autoimmune condition. I take prednisolone, which causes sleep disturbance and cramps. Since starting magnesium and potassium aspartate, my cramps have reduced, bowel function has improved, and I sleep better. I take two capsules at night with food and rate it highly.
Read More
10
Increased sleep quality
I ordered from iHerb for its popularity and good dosage. After a week of taking it, I noticed significant improvements in sleep quality and bowel function. I felt more rested and less irritable during the day. This natural remedy truly works, earning a five-star rating.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
8
Magnesium boosts colonic activity
Effects of oral magnesium sulphate on colonic motility in patients with the irritable bowel syndrome.
Direct focus on IBS treatment
We set out to understand how magnesium sulphate influences the symptoms of irritable bowel syndrome (IBS). In a study involving 20 IBS patients, magnesium sulphate was administered orally, resulting in a quick boost in colonic motor activity. Most participants experienced this increase within just two to six minutes.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Specifically, the percentage of colonic activity rose from 16.2% to 23.7%, signaling a notable change. Those who often felt abdominal pain after eating showed even more pronounced reactions, with their activity jumping from 16.1% to 29.8%. However, it’s important to note that three of these patients still experienced their usual pain after taking magnesium, suggesting that while magnesium can enhance motility, it doesn’t eliminate the pain for everyone.
Ultimately, these findings lend support to the idea that some cases of abdominal pain related to food may stem from heightened intestinal responses to cholecystokinin, a hormone released by the intestine. So while magnesium shows promise for intriguing changes in colonic movement in IBS patients, its effectiveness in alleviating pain remains mixed.
Read More
8
Bile acid sequestrant A3384 shows promise
Effects of conventional and a novel colonic-release bile acid sequestrant, A3384, on fibroblast growth factor 19 and bile acid metabolism in healthy volunteers and patients with bile acid diarrhoea.
Relevant research on BAD treatment
We investigated how a novel colonic-release formulation of colestyramine, A3384, impacts bile acid metabolism and bowel function in patients with primary bile acid diarrhoea (BAD).
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
In a double-blind study, participants received either A3384 or a placebo for two weeks. While conventional bile acid sequestrants lowered serum fibroblast growth factor 19 (FGF19) and increased bile acid production, A3384 did not exhibit this effect.
However, A3384 did improve diarrhoeal symptoms, showing promise as a better-tolerated treatment option for BAD.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.7
10
Increased sleep quality
I ordered from iHerb for its popularity and good dosage. After a week of taking it, I noticed significant improvements in sleep quality and bowel function. I felt more rested and less irritable during the day. This natural remedy truly works, earning a five-star rating.
9.5
Reduced cramps
Magnesium and potassium support heart health, but I've found they help with my autoimmune disease. As I'm on prednisolone, I face side effects like cramps and constipation. Magnesium and potassium aspartate eased my cramps, improved my bowel function, and helped my sleep. I take two capsules at night with a light meal and highly rate this product.
Read More
9.5
Eased eye trembling
I began taking this for trembling in my eyes, and it's the only product that works effectively. It has notably improved my bowel movements, and while caffeine triggers my symptoms, I still enjoy my coffee. Do take care, as the pills are quite large.
9.5
Sleep improvement
Magnesium and potassium support heart function, but they greatly help my autoimmune condition. I take prednisolone, which causes sleep disturbance and cramps. Since starting magnesium and potassium aspartate, my cramps have reduced, bowel function has improved, and I sleep better. I take two capsules at night with food and rate it highly.
Read More
9.5
Improved mood
After a week of taking 1500mg daily, my sleep improved significantly, and my bowel issues were resolved. I felt less irritable and more productive mentally, proving that this supplement works effectively.
